Xiaohua Zhou has also made quite important contributions to the analysis of health care costs. The main difficulty of analyzing health care costs is the four special features of the distribution of health care costs that can cause costs to deviate from normality: 1) many observations with zero costs, 2) kurtosis (heavy tails) because of high-cost observations, and 3) heteroskedasticity. Without taking these characteristics into account, statistical analysis of cost data can be misleading. Xiaohua Zhou and his collaborators have developed a number of new statistical methods for the analysis of healthcare cost, and have published more than 25 papers in top statistical journals such as JASA, Biometrika, Biometrics, etc.
Seleced Pubulications:
- Beste L., Chapko M., Zhou XH., Lee S., Esng X., Maier M.M. Hepatitis C cure is associated with decreased healthcare costs in irrhotics in retrospective Veterans Affairs cohort. Digestive Diseases and Sciences 2018; 63:1454-1462.
- Wang X., Beste L.A., Maier M.M., and Zhou XH. Double robust estimator of average causal treatment effect for censored medical cost data. Statistics in Medicine 2016; 35: 3101-3116.
- Sherwood B., Wang L., Zhou XH. Weighted Quantile Regression for Analyzing Health Care Cost Data with Missing Covariates. Statistics in Medicine 2013; 32: 4967-4979.
- Wang H., Zhou XH. Quantile regression for estimating conditional means of health care costs. Biometrika 2010; 97: 147-158.
- Zhou XH., Lin H., Johnson E. Nonparametric heteroscedastic transformation regression models for skewed data with an application to health care costs. Journal of Royal Statistical Society Series B (JRSS B) 2009; 70: 1029-1047.
- Chapko M. K., Manheim L. M., Guihan M., Sullivan J. H., Zhou XH., Wang L., Mambourg F. J., Hedrick S. C. Assisted Living Pilot Program: Utilization and Cost Finding. Journal of Aging and Health 2009; Vol. 21; pp 208-225.
- Chi Y., Zhou XH. The need for reorientation toward cost-effective prediction. Statistics in Medicine 2008; 27: 182-184.
- Zhou XH., Liang H. Semi-Parametric Single-Index Two-Part Regression Models for Health Care Costs with Zero Values. Computational Statistics & Data Analysis 2006;50(5): 1378-1390.
- Dinh P., Zhou XH. Nonparametric statistical methods for cost-effectiveness analyses. Biometrics 2006; 62: 576-588
- Zhou XH., Qin G., Lin H., Li G. Inferences in censored cost regression models with empirical likelihood. Statistica Sinica 2006, 16: 1213-1232.
- Zhou XH., Qin G., Maciejewski M.L. Estimating the VA health care cost using a semi-parametric heteroscedastic two-part model. Health Serv Outcomes Res Method 2006, 6: 69-80.
- Jiang H., Zhou XH. Bootstrap confidence intervals for medical costs with censored observations. Stat Med 2004; 18: 3365-3376.
- Zhou XH., Ramsey S. Assessing the equality of means of health care costs. Expert review of Pharmacoeconomics and Outcomes Research 2003; 3, 561-567.
- Zhou XH. Inferences about population means of health care costs. Stat Methods Med Res 2002; 11: 327-339.
- Zhou XH, Li C., Gao S., Tierney W.M. Methods for testing equality of means of health care costs in a paired design study. Stat Med 2001; 20:1703-1720.
- Zhou XH, Tu W. Interval estimation for the ratio in means of log-normally distributed medical costs with zero values. Comput Stat Data An 2000; 35(2): 201-210.
- Tu W., Zhou XH. A Wald test comparing medical costs based on log-normal distributions with zero value costs. Stat Med 1999; 18:2749-2762.
- Barkmeier J., Trerotola S.O., Wiebke E., Sherman S., Harris V.J., Snidow J., Johnson M.S., Rogers W., Zhou XH. Percutanenus radiologic, surgical endoscopic, and percutaneous endoscopic gastrostomy/gastrojejunostomy; Comparative study and cost analysis. Cardiovascular and International Radiology. Cardiovasc Intervent Radiol 1998; 21:324-328.
- Zhou XH., Melfi C.A., Hui S. Methods for comparison of Cost Data. Ann Intern Med 1997; 127(8): 752-756.
